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The top selling medicines sold in the US for 2016 - data source Pharmacompass

 

 Type Medicine name Trade name Effective use for Medicine $ Millions in US sales Company

1

Antibody

 Adalimumab Humira Immunology (Organ Transplant, Arthritis etc.) 16078 Abbvie

2

 Chemical mixture Ledipasvir And Sofosbuvir Harvoni Infectious Diseases (HIV, Hepatitis etc.) 9081 Gilead

3

 Chemical Lenalidomide Revlimid  Oncology 6974 Celgene

4

 Antibody Infliximab Remicade  Immunology (Organ Transplant, Arthritis etc.) 6966 Johnson & Johnson

5

 Fusion Protein Etanercept Enbrel Immunology (Organ Transplant, Arthritis etc.) 5965 Amgen

6

 Vaccine Pneumococcal 7-Valent Conjugate Prevnar/Prevenar 13 Anti-Bacterial 5718 Pfizer

7

 Chemical Pregabalin Total Lyrica Neurological/Mental Disorders 4966 Pfizer

8

 Protein Pegfilgrastim Neulasta Blood Disorders 4648 Amgen

9

 Polymer Glatiramer Copaxone Neurological/Mental Disorders 4223 Teva

10

 Chemical Pregabalin Lyrica Ih Neurological/Mental Disorders 4165 Pfizer

11

 Chemical Sofosbuvir Sovaldi  Infectious Diseases (HIV, Hepatitis etc.) 4001 Gilead

12

 Chemical Dimethyl Fumarate Tecfidera Neurological/Mental Disorders 3968 Biogen

13

 Chemical Sitagliptin  Januvia Diabetes 3908 Merck & Co. 

14

 Antibody Nivolumab Opdivo Oncology 3774 Bristol Myers Squibb

15

 Chemical mixture Emtricitabine, And Tenofovir Disoproxil Fumarate Truvada Infectious Diseases (HIV, Hepatitis etc.) 3566 Gilead

16

 Chemical Rosuvastatin Calcium Crestor  Cardiovascular Diseases 3401 AstraZeneca

17

 Chemical Apixaban Eliquis  Blood Disorders 3343 Bristol Myers Squibb

18

 Chemical Imatinib Gleevec/Glivec Oncology 3323 Novartis

19

 Antibody Aflibercept Eylea  Ophthalmology 3323 Regeneron

20

 Antibody Ustekinumab Stelara  Immunology (Organ Transplant, Arthritis etc.) 3232 Johnson & Johnson

21

 Chemical Fingolimod Gilenya Neurological/Mental Disorders 3109 Novartis

22

 Chemical mixture Budesonide And Formoterol Symbicort  Respiratory Disorders 2989 AstraZeneca

23

 Antibody Etanercept Enbrel Immunology (Organ Transplant, Arthritis etc.) 2910 Pfizer

24

 Antibody Eculizumab Soliris  Blood Disorders 2843 Alexion

25

 Protein Onabotulinumtoxina Botox Urology 2786 Allergan

26

 Protein Insulin Lispro  Humalog Diabetes 2769 Eli Lilly

27

 Chemical mixture Efavirenz, Emtricitabine, and Tenofovir Disoproxil Fumarate Atripla Infectious Diseases (HIV, Hepatitis etc.) 2605 Gilead

28

 Chemical Ezetimibe  Zetia Cardiovascular Diseases 2560 Merck & Co. 

29

 Chemical Tadalafil Cialis Sexual Health 2472 Eli Lilly

30

 Protein Interferon Beta-1A Avonex Neurological/Mental Disorders 2314 Biogen

31

 Chemical Rivaroxaban Xarelto  Cardiovascular Diseases 2288 Johnson & Johnson

32

 Chemical Pemetrexed Alimta Oncology 2283 Eli Lilly

33

 Antibody Abatacept Orencia  Immunology (Organ Transplant, Arthritis etc.) 2265 Bristol Myers Squibb

34

 Chemical Abiraterone Acetate Zytiga  Oncology 2260 Johnson & Johnson

35

 Chemical Paliperidone Palmitate Invega Sustenna / Xeplion  Neurological/Mental Disorders 2214 Johnson & Johnson

36

 Chemical mixture Metformin And Sitagliptin Janumet Diabetes 2201 Merck & Co. 

37

 Vaccine Hpv Quadrivalent Vaccine Gardasil / Gardasil 9 Oncology 2173 Merck & Co. 

38

 Chemical Palbociclib Ibrance Oncology 2135 Pfizer

39

 Protein Darbepoetin Alfa Aranesp Blood Disorders 2093 Amgen

40

 Chemical Esomeprazole Magnesium Nexium Gastrointestinal Disorders 2032 AstraZeneca

41

 Chemical Lisdexamfetamine Dimesylate Vyvanse Neurological/Mental Disorders 2014 Shire

42

 Antibody Natalizumab Tysabri Neurological/Mental Disorders 1964 Biogen

43

 Chemical mixture Cobicistat, Elvitegravir, Emtricitabine And Tenofovir Disoproxil Fumarate Stribild Infectious Diseases (HIV, Hepatitis etc.) 1914 Gilead

44

 Chemical Darunavir Prezista  Infectious Diseases (HIV, Hepatitis etc.) 1851 Johnson & Johnson

45

 Antibody Ranibizumab Lucentis Ophthalmology 1835 Novartis

46

 Chemical Ibrutinib Imbruvica Oncology 1832 Abbvie

47

 Chemical Dasatinib Sprycel Oncology 1824 Bristol Myers Squibb

48

 Chemical Atorvastatin Calcium Lipitor Cardiovascular Diseases 1758 Pfizer

49

 Chemical Sofosbuvir And Velpatasvir Epclusa Infectious Diseases (HIV, Hepatitis etc.) 1752 Gilead

50

 Antobody Golimumab Simponi/Simponi Aria  Immunology (Organ Transplant, Arthritis etc.) 1745 Johnson & Johnson