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Budesonide (Molecule of the Month for May 2017)

Pulmicort, Rhinocort, Entocort,

Budesonide is nebulized for maintenance and prophylactic treatment of asthma including patients who require oral corticosteroids and those who may benefit from a systemic dose reduction.It is available as an inhaler, pill, nasal spray, and rectal forms. The inhaled form is used in the long-term management of asthma and chronic obstructive pulmonary disease (COPD). The nasal spray is used for allergic rhinitis and nasal polyps. The pills in a delayed release form and rectal forms may be used for inflammatory bowel disease including Crohn's disease, ulcerative colitis and microscopic colitis.

Formulations of delayed-release Budesonide are an effective treatment for mild-to-moderately active Crohn's disease involving the ileum and/or ascending colon A Cochrane review found evidence for up to 3 months (but not longer) of maintenance of remission Crohn's disease.

Those taking tablets or capsules orally should avoid grapefruit juice and echinacea. Grapefruit juice may double bioavailability of oral budesonide. Echinacea diminishes bioavailability.

Formal Chemical Name (IUPAC)



Picture of Budesonide 3D model

click on the picture of  Budesonide above to interact
with the 3D model of the
Budesonide structure
(this will open a new browser window)

Picture of Budesonide


Update by Karl Harrison
(Molecule of the Month for May 2017 )

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