Picture of Cyclooxygenase

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Cyclooxygenase structure
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Picture of Cyclooxygenase

Cyclooxygenase (COX-2) keeps blood vessels open and flowing in areas where there is tissue damage or swelling that often occurs around certain cancerous growths. Again, by cutting off the necessary blood supply by inhibiting the COX, the cancerous cells may not survive.

Find out more about the ScreenSaver LifeSaver project http://www.chem.ox.ac.uk/curecancer.html

The protein structures are from the RSCB Protein Data Bank. with a reference H.M.Berman, J.Westbrook, Z.Feng, G.Gilliland, T.N.Bhat, H.Weissig, I.N.Shindyalov, P.E.Bourne: The Protein Data Bank. Nucleic Acids Research, 28 pp. 235-242 (2000)

Formal Chemical Name (IUPAC)

References

http://www.rcsb.org/pdb

Update by Karl Harrison
(Molecule of the Month for April 2001 )