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Mannose (Molecule of the Month for March 2008)

Hexose, Sugar



Mannose is a hexose sugar monomer. Mannose is present in numerous glycoconjugates including N-linked glycosylation of proteins. C-mannosylation is also abundant and can be found in collage-like regions. The name of both "mannose" and "manitol" comesis manna, which the Bible records as the food supplied to the Israelites during their journey through the Sinai Peninsula. Manna is a sweet secretion of several trees and shrubs, such as Fraxinus ornus.

D-Mannose, which appears in some fruits including cranberry, has been postulated to prevent the adhesion of bacteria to the epithelium of the urinary tract and Urinary bladder through a mechanism presumed to be competitive in nature with the polysaccharide coating of the cystic epithelium.

Formal Chemical Name (IUPAC)
(2S,3S,4S,5S,6R)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

References

http://en.wikipedia.org/wiki/Mannose

Picture of Mannose

click on the picture above to interact
with the 3D model of the
Mannose structure
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Picture of Mannose

C6 H12 O6



Update by Karl Harrison
(Molecule of the Month for March 2008 )