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Diflunisal (Molecule of the Month for January 2006)


Diflunisal is used to relieve mild to moderate pain and to reduce the pain and inflammation (swelling) caused by arthritis or other inflammatory conditions. Diflunisal is a non steroidal anti inflammatory Drug ( NSAID ). Diflunisal acts by inhibiting the production of prostaglandin, a hormone that creates inflammation and stimulates the neuro receptors for pain.

Diflunisal is a difluorophenyl derivative of aspirin (salicylic acid). Diflunisal is not metabolized to salicylic acid.

Formal Chemical Name (IUPAC)
4',6'-difluoro-4-hydroxybiphenyl-3-carboxylic acid



Picture of Diflunisal

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Diflunisal structure
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Picture of Diflunisal


Update by Karl Harrison
(Molecule of the Month for January 2006 )