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Chloramphenicol (Molecule of the Month for January 2006)



Chloramphenicol is an antibiotic that was derived from the bacterium Streptomyces venezuelae, though now is produced synthetically. Chloramphenicol act as an antibiotic against a wide variety of microorganisms, but due to serious side-effects in humans, it is usually reserved for the treatment of serious and life-threatening infections (e.g., cholera and typhoid fever).

Chloramphenicol is also used in external treatments such as eye drops or ointment to treat bacterial conjunctivitis.

Chloramphenicol stops bacterial growth by binding to the bacterial ribosome and inhibiting protein synthesis.

Formal Chemical Name (IUPAC)
2,2-dichloro-N-((1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl)acetamide

References

http://en.wikipedia.org/wiki/Chloramphenicol

Picture of Chloramphenicol 3D model

click on the picture of  Chloramphenicol above to interact
with the 3D model of the
Chloramphenicol structure
(this will open a new browser window)

Picture of Chloramphenicol

C11H12Cl2N2O5



Update by Karl Harrison
(Molecule of the Month for January 2006 )

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