RAS proteins (Molecule of the Month for April 2001)
Screensaver Lifesaver Proteins
RAS proteins give a chemical "message" that activate cell growth. Without this signaling factor, the cell doesn't "know" to grow. Inhibiting RAS in cancer cells means an end to their uncontrolled growth.
Find out more about the ScreenSaver LifeSaver project http://www.chem.ox.ac.uk/curecancer.html
The protein structures are from the RSCB Protein Data Bank. with a reference H.M.Berman, J.Westbrook, Z.Feng, G.Gilliland, T.N.Bhat, H.Weissig, I.N.Shindyalov, P.E.Bourne: The Protein Data Bank. Nucleic Acids Research, 28 pp. 235-242 (2000)
Formal Chemical Name (IUPAC)
Update by Karl Harrison
(Molecule of the Month for April 2001 )