Cyclooxygenase (Molecule of the Month for April 2001)
Screensaver Lifesaver Proteins
Cyclooxygenase (COX-2) keeps blood vessels open and flowing in areas where there is tissue damage or swelling that often occurs around certain cancerous growths. Again, by cutting off the necessary blood supply by inhibiting the COX, the cancerous cells may not survive.
Find out more about the ScreenSaver LifeSaver project http://www.chem.ox.ac.uk/curecancer.html
The protein structures are from the RSCB Protein Data Bank. with a reference H.M.Berman, J.Westbrook, Z.Feng, G.Gilliland, T.N.Bhat, H.Weissig, I.N.Shindyalov, P.E.Bourne: The Protein Data Bank. Nucleic Acids Research, 28 pp. 235-242 (2000)
Formal Chemical Name (IUPAC)
Update by Karl Harrison
(Molecule of the Month for April 2001 )