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Cyclooxygenase (Molecule of the Month for April 2001)

Screensaver Lifesaver Proteins



Cyclooxygenase (COX-2) keeps blood vessels open and flowing in areas where there is tissue damage or swelling that often occurs around certain cancerous growths. Again, by cutting off the necessary blood supply by inhibiting the COX, the cancerous cells may not survive.

Find out more about the ScreenSaver LifeSaver project http://www.chem.ox.ac.uk/curecancer.html

The protein structures are from the RSCB Protein Data Bank. with a reference H.M.Berman, J.Westbrook, Z.Feng, G.Gilliland, T.N.Bhat, H.Weissig, I.N.Shindyalov, P.E.Bourne: The Protein Data Bank. Nucleic Acids Research, 28 pp. 235-242 (2000)

Formal Chemical Name (IUPAC)

References

http://www.rcsb.org/pdb

Picture of Cyclooxygenase 3D model

click on the picture of  Cyclooxygenase above to interact
with the 3D model of the
Cyclooxygenase structure
(this will open a new browser window)

Picture of Cyclooxygenase



Update by Karl Harrison
(Molecule of the Month for April 2001 )

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