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Superoxide dismutase (Molecule of the Month for April 2001)

Screensaver Lifesaver Proteins

Superoxide dismutase (SOD) is an enzyme that removes the superoxide (O2-) radical. We hear a lot in nutritional news about "antioxidants". Think of SOD as a natural antioxidant. Since cancer cells produce more oxidants than normal cells, they can basically oxidize themselves to death. That is why SOD is a target protein if SOD is inhibited in the cancer cell, the cancer cells are damaged, controlling growth

Find out more about the ScreenSaver LifeSaver project http://www.chem.ox.ac.uk/curecancer.html

The protein structures are from the RSCB Protein Data Bank. with a reference H.M.Berman, J.Westbrook, Z.Feng, G.Gilliland, T.N.Bhat, H.Weissig, I.N.Shindyalov, P.E.Bourne: The Protein Data Bank. Nucleic Acids Research, 28 pp. 235-242 (2000)

Formal Chemical Name (IUPAC)



Picture of Superoxide dismutase

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Superoxide dismutase structure
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Picture of Superoxide dismutase

Update by Karl Harrison
(Molecule of the Month for April 2001 )