Protein-Tyrosine-Phosphatase 1B (Molecule of the Month for April 2001)
Screensaver Lifesaver Proteins
This is one of the protein tyrosine phosphatases which play a role in regulating cellular events. It is conceivable that inhibition of this protein will enable apoptosis (death of cancer cells).
Find out more about the ScreenSaver LifeSaver project http://www.chem.ox.ac.uk/curecancer.html
The protein structures are from the RSCB Protein Data Bank. with a reference H.M.Berman, J.Westbrook, Z.Feng, G.Gilliland, T.N.Bhat, H.Weissig, I.N.Shindyalov, P.E.Bourne: The Protein Data Bank. Nucleic Acids Research, 28 pp. 235-242 (2000)
Formal Chemical Name (IUPAC)
Update by Karl Harrison
(Molecule of the Month for April 2001 )