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C-ABL Tyrosine Kinase (Molecule of the Month for April 2001)

Screensaver Lifesaver Proteins

This is a mutant protein commonly expressed in chronic leukemia. It has been suggested that inhibition of the protein can not only prevent the development of Leukemia but shrink certain tumours.

Find out more about the ScreenSaver LifeSaver project http://www.chem.ox.ac.uk/curecancer.html

The protein structures are from the RSCB Protein Data Bank. with a reference H.M.Berman, J.Westbrook, Z.Feng, G.Gilliland, T.N.Bhat, H.Weissig, I.N.Shindyalov, P.E.Bourne: The Protein Data Bank. Nucleic Acids Research, 28 pp. 235-242 (2000)

Formal Chemical Name (IUPAC)



Picture of C-ABL Tyrosine Kinase

click on the picture above to interact
with the 3D model of the
C-ABL Tyrosine Kinase structure
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Picture of C-ABL Tyrosine Kinase

Update by Karl Harrison
(Molecule of the Month for April 2001 )